The side effects of large dosages are refuted with much scientifically proven evidences. On the contrary large dosages are often needed for a sick person and has very successful results almost always. If you take vitamins and at the same time take medications, seek advice from a doctor since sometimes the medications must be reduced when vitamins are taken. If a person has high blood pressure the Vitamin E dosage must begin small, something like 100 Units for perhaps a week or two to be raised in intervals. That is around 10 times more than USRDA and considered a very small dosage according to the book. 

Chlorine in drinking water and elsewhere depletes the body of Vitamin E. This could be one of the main reasons for the steady increase of many modern diseases like Heart diseases, Arteriosclerosis, High blood pressure, Diabetes. Bad Immunity defense, Birth defects, Mental health, Bad Memory, Migraine, Stroke, Infertility, Allergies, Auto immune diseases, Asthma, Aches and pains, Arthritis,  Cramps, High cholesterol, Stillbirths, Skin diseases etc. etc. Allah has created at least one cure for every disease and Vitamin E can be an important one of them. Allah knows best. 

It seems that Vitamin E should come not only from synthetic resources. Vitamin E is not only tocopherols, alfa, beta, gamma, delta but also tocotrienols, alfa, beta, gamma, delta. According to some sources Tocotrienols are more efficient than even Tocopherols. Synthetic pills often contain only tocopherol-Alfa. Tocotrienols can be found in Barley, wheatgerms, rice, oats, bran oil, olive oil, almond oil and especially palm oil. If you want a nice variety of palm oil rich also in betacarotines try something else than Carotino since it is mixed with Canola which most probably is GMO.

Try Nutrolein instead: from Unitata Berhad 36009 Teluk Intan, Perak MALAYSIA

or: Carotene: from Ecogreen Farms Sdn Bhd, 125 Jalan Aminuddin Baki, Taman Tun Dr. Ismail 60000 Kuala Lumpur, tel 03-772-8388, fax: 03-7729-3417, http://www.ecogreen.com.my

However the strength of natural sources might not be enough for a person who is sick or who is old or for other reasons cannot absorb enough amounts of the vitamin. When we are sick we need extra much of vitamins. When we are sick we must have extra supplements. The diet, especially the modern diet, is not enough. But then take preferably Tocotrienol in the local brand TOCOVID instead of the sometimes synthetic Vitamin-E that sometimes even might be GMO containing exclusively synthetic Tocopherol, common in vitamin shops

Vitamin E does not work on it's own without the presence of enough of good quality minerals in a form that can be utilized by the body. If we live on a diet of junk food or only cooked and fried food we don't get enough of good quality minerals in our food. Most minerals from vitamin shops are in the wrong form, almost useless for the body at least if we are over 50 years old. Fresh raw plants and fruits from organic quality farming have enough of minerals and in a form that can be utilized 100% in the body by anybody independent of age.